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MicroRNAs in apoptosis, autophagy and necroptosis.

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成果类型:
期刊论文
作者:
Su, Zhenyi;Yang, Zuozhang;Xu, Yongqing;Chen, Yongbin;Yu, Qiang
通讯作者:
Yang, ZZ
作者机构:
[Chen, Yongbin] Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
[Yu, Qiang] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
[Yang, Zuozhang] Bone and Soft Tissue Tumors Research Center of Yunnan Province, Department of Orthopaedics, the Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, Yunnan 650118, China
[Yang, Zuozhang; Xu, Yongqing] Department of Orthopaedics, Kunming General Hospital of Chengdu Military Command, Kunming, Yunnan 650118, China
[Su, Zhenyi] Department of Biochemistry and Molecular Biology, Medical School, Southeast University, Nanjing, Jiangsu 210009, China
通讯机构:
[Yang, ZZ] Kunming Med Univ, Tumor Hosp Yunnan Prov, Bone & Soft Tissue Tumors Res Ctr Yunnan Prov, Dept Orthopaed,Affiliated Hosp 3, Kunming 650118, Yunnan, Peoples R China.
语种:
英文
关键词:
microRNA;apoptosis;autophagy;necroptosis;cancer progression
期刊:
Oncotarget
ISSN:
1949-2553
年:
2015
卷:
6
期:
11
页码:
8474-8490
文献类别:
WOS:Article
所属学科:
ESI学科类别:分子生物学&遗传学;WOS学科类别:Cell Biology;Oncology
入藏号:
WOS:000358774600005;PMID:25893379
基金类别:
National Natural Science Foundation of China [81460440, 31300666, 81260322, 81372322]; Natural Science Foundation of Yunnan Province [2012FB163]; Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical University [2014FB059]; Specialty Fund of High-level Talents Medical Personnel Training of Yunnan Province [D-201242]
机构署名:
本校为通讯机构
院系归属:
基础医学院
临床肿瘤学院
摘要:
MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for cleavage or translational repression. Numerous miRNAs regulate programmed cell death including apoptosis, autophagy and necroptosis. We summarize how miRNAs regulate apoptotic, autophagic and necroptotic pathways and cancer progression. We also discuss how miRNAs link different types of cell death.
参考文献:
Alahari SK., 2013, REGULATION METASTASI, P81
Alajez NM, 2011, CANCER RES, V71, P2381, DOI 10.1158/0008-5472.CAN-10-2754
Frankel LB, 2012, CARCINOGENESIS, V33, P2018, DOI 10.1093/carcin/bgs266
Oberst A, 2011, NATURE, V471, P363, DOI 10.1038/nature09852
Sun LM, 2012, CELL, V148, P213, DOI 10.1016/j.cell.2011.11.031

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