版权说明 帮助中心 进入管理中心
首页 > 成果 > 详情

Apoptosis, autophagy, necroptosis, and cancer metastasis.

ESI高被引SCI-EMedline
WOS被引频次:133
认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Su, Zhenyi*;Yang, Zuozhang*;Xu, Yongqing*;Chen, Yongbin*;Yu, Qiang*
通讯作者:
Su, Zhenyi;Su, Zhenyi;Yang, Zuozhang;Yang, Zuozhang;Xu, Yongqing;Chen, Yongbin;Yu, Qiang
作者机构:
[Chen, Yongbin] Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China. ybchen@mail.kiz.ac.cn
[Yu, Qiang] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China. qyu@sibs.ac.cn
[Yang, Zuozhang] Bone and Soft Tissue Tumors Research Center of Yunnan Province, Department of Orthopaedics, the Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, Yunnan, 650118, China. yangzuozhang@163.com
[Yang, Zuozhang] Department of Orthopaedics, Kunming General Hospital of Chengdu Military Command, Kunming, Yunnan, 650118, China. yangzuozhang@163.com
[Xu, Yongqing] Department of Orthopaedics, Kunming General Hospital of Chengdu Military Command, Kunming, Yunnan, 650118, China. xuyongqingkm@163.net
通讯机构:
[Yu, Qiang] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
[Su, Zhenyi] Department of Biochemistry and Molecular Biology, Medical School, Southeast University, Nanjing, Jiangsu, 210009, China.
[Su, Zhenyi] Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.
[Chen, Yongbin] Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China.
[Yang, Zuozhang] Bone and Soft Tissue Tumors Research Center of Yunnan Province, Department of Orthopaedics, the Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming, Yunnan, 650118, China.
语种:
英文
关键词:
Apoptosis;Autophagy;Necroptosis;Metastasis
期刊:
MOLECULAR CANCER
ISSN:
1476-4598
年:
2015
卷:
14
页码:
48
文献类别:
WOS:Review
所属学科:
ESI学科类别:分子生物学&遗传学;WOS学科类别:Biochemistry & Molecular Biology;Oncology
入藏号:
WOS:000350509500001;PMID:25743109
基金类别:
National Natural Science Foundation of China [81460440, 31300666, 81260322, 81372322]; first Class General Financial Grant from the China Postdoctoral Science Foundation [2013M542478]; Natural Science Foundation of Yunnan Province [2012FB163]; Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical University [2014FB059]; Specialty Fund of High-level Talents Medical Personnel Training of Yunnan Province [D-201242]
机构署名:
本校为通讯机构
院系归属:
基础医学院
临床肿瘤学院
摘要:
Metastasis is a crucial hallmark of cancer progression, which involves numerous factors including the degradation of the extracellular matrix (ECM), the epithelial-to-mesenchymal transition (EMT), tumor angiogenesis, the development of an inflammatory tumor microenvironment, and defects in programmed cell death. Programmed cell death, such as apoptosis, autophagy, and necroptosis, plays crucial roles in metastatic processes. Malignant tumor cells must overcome these various forms of cell death to metastasize. This review summarizes the recent advances in the understanding of the mechanisms by which key regulators of apoptosis, autophagy, and necroptosis participate in cancer metastasis and discusses the crosstalk between apoptosis, autophagy, and necroptosis involved in the regulation of cancer metastasis.
参考文献:
Adorno M, 2009, CELL, V137, P87, DOI 10.1016/j.cell.2009.01.039
Amaravadi RK, 2007, CLIN CANCER RES, V13, P7271, DOI 10.1158/1078-0432.CCR-07-1595
Apetoh L, 2007, NAT MED, V13, P1050, DOI 10.1038/nm1622
Azab F, 2013, BLOOD, V122, P3011
Bai LC, 2014, ANNU REV MED, V65, P139, DOI 10.1146/annurev-med-010713-141310

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com